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Cell potency is a cell's ability to differentiate into other cell types. [1] [2] The more cell types a cell can differentiate into, the greater its potency.Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally ...
The liver receptor homolog-1 (LRH-1) also known as totipotency pioneer factor NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. [ 5 ] [ 6 ] LRH-1 is a member of the nuclear receptor family of intracellular transcription factors .
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Teratoma formation is a landmark test for pluripotency. Embryoid body: hESCs in culture spontaneously form ball-like embryo-like structures termed " embryoid bodies ", which consist of a core of mitotically active and differentiating hESCs and a periphery of fully differentiated cells from all three germ layers. iPSCs also form embryoid bodies ...
To test this prediction, the authors conducted whole-genome profiling of DNA methylation patterns in several human embryonic stem cell (ESC), iPSC, and progenitor cell lines. Female adipose cells, lung fibroblasts , and foreskin fibroblasts were reprogrammed into induced pluripotent state with the OCT4 , SOX2 , KLF4 , and MYC genes.
A test setup suitable for testing receivers at microwave frequencies is shown in the figure. The two signal generators, F1 and F2, are combined using a directional coupler in reverse. That is, the two generators are connected to what would normally be the coupled and transmitted output ports respectively.
Gottlieb Haberlandt (28 November 1854 – 30 January 1945) was an Austrian botanist.He was the son of European 'soybean' pioneer Professor Friedrich J. Haberlandt. [1] His son Ludwig Haberlandt was an early reproductive physiologist now given credit as the 'grandfather' of the birth control pill.
Least-squares spectral analysis (LSSA) is a method of estimating a frequency spectrum based on a least-squares fit of sinusoids to data samples, similar to Fourier analysis. [ 1 ] [ 2 ] Fourier analysis, the most used spectral method in science, generally boosts long-periodic noise in the long and gapped records; LSSA mitigates such problems. [ 3 ]