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CT scan in a patient with acinar cell carcinoma. The disease is more common in men than women and the average age at diagnosis is about 60. [2] Symptoms are often non-specific and include weight loss. A classic presentation, found in around 15% of cases includes subcutaneous nodules (due to fat necrosis) and arthralgias, caused by a release of ...
Acinar adenocarcinoma. Acinar adenocarcinoma is a histological subtype of gland-forming cancer that is diagnosed when cuboidal and/or columnar shaped malignant cells in the neoplastic tissue form acini and tubules. [1] It is a common form of cancer occurring in the lung and prostate gland.
Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases. Often appears pseudoencapsulated.
Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. [1] Treatment options are partly based on the cancer stage. [1] Surgery is the only treatment that can cure pancreatic adenocarcinoma, [12] and may also be done to improve quality of life without the potential for cure.
Autoimmune Pancreatitis (AIP) is an increasingly recognized type of chronic pancreatitis that can be difficult to distinguish from pancreatic carcinoma but which responds to treatment with corticosteroids, particularly prednisone. [1] Although autoimmune pancreatitis is quite rare, it constitutes an important clinical problem for both patients ...
James Paget. Paget's disease of the breast (also known as mammary Paget's disease) is a rare skin change at the nipple nearly always associated with underlying breast cancer. [2] Paget's disease of the breast was first described by Sir James Paget in 1874. [3] The condition is an uncommon disease accounting for 1 to 4% of all breast cancers cases.
The metaplastic epithelial is at the junction (center of image) and has an intensely eosinophilic (bright pink) cytoplasm. H&E stain. Specialty. Oncology. Pancreatic acinar metaplasia (PAM) is a common incidental histopathologic finding present in approximately 20-25% of patients undergoing an esophagogastroduodenoscopy. [1][2]
Resected pancreatoblastomas can be quite large, ranging from 2 centimeters to 20 centimeters in size (1 to 8 inches). They are typically solid, soft masses. Under the microscope, at least two cell types are seen: cells with “acinar” differentiation, and cells forming small “squamoid” nests. The cells with acinar differentiation have ...