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In a study using the anti-depressant clomipramine, nine dogs underwent withdrawal after discontinuing treatment. Five of those dogs were successful in overcoming the withdrawal, while four dogs relapsed. Although the study's sample sizes were relatively small, it illuminated one of the many variables regarding psychoactive drug withdrawal.
Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
Noise phobia in dogs. Dog noise phobia, along with dog noise anxiety, are terms sometimes used by dog owners and veterinarians to describe canine fear of, and the corresponding stress responses to, loud noises. Noise-related phobia are common in dogs, and may be triggered by fireworks, thunderstorms, gunshots, and even bird noises.
Acepromazine. Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and ...
dexamethasone – anti-inflammatory steroid. diazepam – benzodiazepine used to treat status epilepticus, also used as a preanaesthetic and a sedative. dichlorophene – fungicide, germicide, and antimicrobial agent, also used for the removal of parasites. diphenhydramine – histamine blocker. doxycycline – antibiotic, also used to treat ...
Pharmaceutically, clomipramine was found to be more effective than an alternative chemical, amitriptyline, in treatments for dogs. One study by Karen Overall discovered that by combining behavioral therapy with the more effective clomipramine, the symptoms of Canine Compulsive Disorder decreased by over 50% for all of the dogs involved in the ...
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