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Sinus node dysfunction also known as sick sinus syndrome is a group of irregular heartbeat conditions caused by faulty electrical signals of the heart. When the heart's sinoatrial node is defective, the heart's rhythms become abnormal—typically too slow or exhibiting pauses in its function or a combination, and very rarely faster than normal ...
The ability of baroreflex activation therapy to reduce sympathetic nerve activity suggests a potential in the treatment of chronic heart failure, because in this condition there is often intense sympathetic activation and patients with such sympathetic activation show a markedly increased risk of fatal arrhythmias and death. [citation needed]
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that causes episodes of increased activity of the sympathetic nervous system. Hyperactivity of the sympathetic nervous system can manifest as increased heart rate, increased respiration, increased blood pressure, diaphoresis , and hyperthermia . [ 1 ]
An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.
heart arrhythmia – decrease the output of sinus node thus stabilizing heart function; coronary artery disease – reduce heart rate and hence increasing oxygen supply; heart failure – prevent sudden death related to this condition, [7] which is often caused by ischemias or arrhythmias [21] hyperthyroidism – reduce peripheral sympathetic ...
Accelerans nerve forms a part of the sympathetic branch of the autonomic nervous system, and its function is to release noradrenaline at its endings on the heart. The heart beats according to a rhythm set up by the sinus-atrial node or pacemaker , which is located on the right atrium of the heart.
In a whole, it is the heart's reaction to catecholamines (norepinephrine, epinephrine, dopamine). Conditions that decrease bathmotropy (i.e. hypercarbia) cause the heart to be less responsive to catecholaminergic drugs. A substance that has a bathmotropic effect is known as a bathmotrope.
Accelerator nerves are cardiopulmonary splanchnic nerves that allow the sympathetic nervous system's stimulation of the heart. They originate from the ganglion cells of the superior, middle, and inferior cervical ganglion of the sympathetic trunk. [1] The accelerator nerves increase the heart rate.