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Trichophyton rubrum is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, [ 2 ] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot , fungal infection of nail, jock itch , and ringworm worldwide. [ 3 ]
Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia .
[8] Infection may become chronic and widespread if the host has a compromised immune system and is receiving treatment that reduces T-lymphocyte function. [8] Also, the responsible species for chronic infections in both normal and immunocompromised patients tends to be Trichophyton rubrum; immune response tends to be hyporeactive. [8]
Onychomycosis (also known as "dermatophytic onychomycosis", or "tinea unguium" [2] is a fungal infection of the nail. [8] It is the most common disease of the nails and constitutes about half of all nail abnormalities. [9] This condition may affect toenails or fingernails, but toenail infections are particularly common. It occurs in about 10% ...
Athlete's foot is most commonly caused by the molds known as Trichophyton rubrum and T. mentagrophytes, [22] but may also be caused by Epidermophyton floccosum. [23] [24] Most cases of athlete's foot in the general population are caused by T. rubrum; however, the majority of athlete's foot cases in athletes are caused by T. mentagrophytes. [13]
Superficial scrapes of skin examined underneath a microscope may reveal the presence of a fungus.This is done by utilizing a diagnostic method called KOH test, [6] wherein the skin scrapings are placed on a slide and immersed on a dropful of potassium hydroxide solution to dissolve the keratin on the skin scrappings thus leaving fungal elements such as hyphae, septate or yeast cells viewable.
Trichophyton mentagrophytes is a species in the fungal genus Trichophyton. [1] It is one of three common fungi which cause ringworm in companion animals.It is also the second-most commonly isolated fungus causing tinea infections in humans, and the most common or one of the most common fungi that cause zoonotic skin disease.
The hair perforation test, also known as an in vitro hair perforation test, is a laboratory test used to help distinguish the isolates of dermatophytes, such as Trichophyton mentagrophytes and its variants. [1]