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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
Biguanide. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ?) Biguanide (/ baɪˈɡwɒnaɪd /) is the organic compound with the formula HN (C (NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution.
Ropinirole. Ropinirole, sold under the brand name Requip among others, is a medication used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). [3] It is taken by mouth. [4] Common side effects include sleepiness, vomiting, and dizziness. [4] Serious side effects may include pathological gambling, low blood pressure with ...
Guanfacine. Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. [3][9] Guanfacine is FDA-approved for monotherapy treatment of ADHD, [3] as well as being used for ...
Phenibut. US: Unapproved drug; use in dietary supplements, food, or medicine is unlawful. [4] Phenibut, sold under the brand name Anvifen among others, [1] is a central nervous system (CNS) depressant with anxiolytic effects, and is used to treat anxiety, insomnia, and for a variety of other indications. [5]
[8] [9] The estimated relative potency of nefopam to morphine indicates that 20 mg of nefopam HCl is the approximate analgesic equal of 12 mg of morphine with comparable analgesic efficacy to morphine, [10] [11] [12] or oxycodone, [13] while nefopam tends to produce fewer side effects, does not produce respiratory depression, [14] and has much ...
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use, [4] it is spelled polihexanide (INN) and sold under various brand names. [5] PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus ...
Adverse effect incidence [2] [5] [6] [16] [17]. Common (>1% incidence) adverse effects include. Extrapyramidal side effects such as: (which usually become apparent soon after therapy is begun or soon after an increase in dose is made)