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The natural history of disease is the course a disease takes in individual people from its pathological onset ("inception") until its resolution (either through complete recovery or eventual death). [1] The inception of a disease is not a firmly defined concept. [1]
In medicine, a natural history study is a study that follows a group of people over time who have, or are at risk of developing, a specific medical condition or disease. A natural history study collects health information over time to understand how the medical condition or disease develops and to give insight into how it might be treated.
Natural history is a domain of inquiry involving organisms, including animals, fungi, and plants, in their natural environment, leaning more towards observational than experimental methods of study. A person who studies natural history is called a naturalist or natural historian. Natural history encompasses scientific research but is not ...
The course of a disease, also called its natural history, [3] is the development of the disease in a patient, including the sequence and speed of the stages and forms they take. [4] Typical courses of diseases include: chronic; recurrent or relapsing; subacute: somewhere between an acute and a chronic course
A prospective study would involve following the case series over time to evaluate the disease's natural history. [ 51 ] The latter type, more formally described as self-controlled case-series studies, divide individual patient follow-up time into exposed and unexposed periods and use fixed-effects Poisson regression processes to compare the ...
Additionally, even within a given culture, time plays a role in defining disease caused by natural forces and imbalances. For example, as recently as the 20th century homosexuality was considered a biologically determined disease by the American Psychiatric Association and World Health Organization based on social rather than pathological premises.
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A secondary disease is a disease that is a sequela or complication of a prior, causal disease, which is referred to as the primary disease or simply the underlying cause . For example, a bacterial infection can be primary, wherein a healthy person is exposed to bacteria and becomes infected, or it can be secondary to a primary cause, that ...