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Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Frailty or frailty syndrome refers to a state of health in which older adults gradually lose their bodies' in-built reserves and functioning. This makes them more vulnerable, less able to recover and even apparently minor events (infections, environmental changes) can have drastic impacts on their physical and mental health.
Several other notable individuals with Chronic fatigue syndrome are interviewed, and they clearly express their lengthy "excruciating misery" in battling the illness. The interviews included movie director Blake Edwards , United States Olympic soccer gold medalist Michelle Akers , and a high school senior in Connecticut, bedridden for two years ...
Excessive daytime sleepiness (EDS) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep.
This allows ICF to be coded as fatigue or unspecified chronic fatigue, and help distinguish it from other forms of fatigue including cancer-related fatigue, chronic fatigue syndrome, fatigue due to depression, fatigue due to old age, weakness/asthenia, and in the ICD-10, also from fatigue lasting under 6 months.
A chronic sleep-restricted state adversely affects the brain and cognitive function. [8] However, in a subset of cases, sleep deprivation can paradoxically lead to increased energy and alertness; although its long-term consequences have never been evaluated, sleep deprivation has even been used as a treatment for depression .
Fatigue is a state of tiredness (which is not sleepiness), exhaustion [1] or loss of energy. [ 2 ] [ 3 ] Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease , organ failure , chronic pain conditions, mood disorders , heart disease , infectious diseases , and post-infectious-disease states ...
There are many proposed causes of sarcopenia and it is likely the result of multiple interacting factors. Understanding of the causes of sarcopenia is incomplete, however, changes in hormones, immobility, age-related muscle changes, nutrition, and neurodegenerative changes have all been recognized as potential causative factors.
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