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  2. Narcolepsy - National Institute of Neurological Disorders and...

    www.ninds.nih.gov/health-information/disorders/narcolepsy

    Narcolepsy is a chronic neurological disorder that affects the brain’s ability to control sleep-wake cycles. People with narcolepsy may feel rested after waking, but then feel very sleepy throughout much of the day.

  3. Narcolepsy Fast Facts - Narcolepsy Network

    narcolepsynetwork.org/about-narcolepsy/narcolepsy-fast-facts

    Narcolepsy affects an estimated 1 in every 2,000 people in the United States. That’s 200,000 Americans and approximately 3 million worldwide. It is estimated that only 25% of people who have narcolepsy have been diagnosed and are receiving treatment.

  4. Narcolepsy is a disorder of rapid onset rapid eye movement (REM) sleep characterized by excessive daytime sleepiness (EDS), frequent uncontrollable sleep attacks as well as sleep fragmentation and can be associated with cataplexy, sleep paralysis, and hypnagogic hallucinations.

  5. The primary objective was to describe trends in the 2-year limited duration prevalence of narcolepsy from 20132016 in a large insured population with claims activity. Secondary objectives were to assess the prevalence of other sleep disorders and the frequency of diagnostic sleep testing.

  6. Current and Future Treatment Options for Narcolepsy: A Review

    pmc.ncbi.nlm.nih.gov/articles/PMC5611768

    The AASM Narcolepsy Quality Measures Workgroup was charged with developing quality measures in order to enhance the care of patients with narcolepsy 21. Three outcome measures that are crucial for successful treatment were identified, along with seven process measures.

  7. Narcolepsy | New England Journal of Medicine

    www.nejm.org/doi/full/10.1056/NEJMra1500587

    Narcolepsy affects approximately 1 in 2000 people but is often not correctly diagnosed. This review article summarizes recent discoveries regarding the neurobiologic features of this...

  8. Findings are reported per age, continent, and proxy race/ethnicity as well as period (i.e., before/after the pandemic). This meta-review showed that narcolepsy occurs in 0.87-1.21 of the world population, with specifically NT1 being investigated. Its pooled incidence rate in vaccinated samples is 1.58.

  9. Narcolepsy is a rare and often disabling hypothalamic disorder that presents with sleep–wake dysregulation (excessive daytime sleepiness (EDS), cataplexy, hallucinations, sleep paralysis and...

  10. Increased Mortality in Narcolepsy - PMC - National Center for ...

    www.ncbi.nlm.nih.gov/pmc/articles/PMC3920308

    The narcolepsy population had consistently higher mortality rates relative to those without narcolepsy across all age groups, stratified by age decile, from 25-34 years to 75+ years of age. The SMR for females with narcolepsy was lower than for males with narcolepsy. Conclusions:

  11. Narcolepsy is a rare condition affecting 37.7/100,000 individuals (126,191 individuals in the current US population). Our US general population prevalence is in line with rates found in community-based studies but lower than what is reported in claim database studies.