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Notably the capsaicin used for the relief of neuropathic pain is a substantially higher concentration than capsaicin creams available over the counter, there is no evidence that over the counter capsaicin cream can improve neuropathic pain [56] and topical capsaicin can itself induce pain. [55]
Mirogabalin, under the brand name Tarlige, was approved for the treatment of neuropathic pain and postherpetic neuralgia in Japan in January 2019. [ 57 ] A longitudinal trend study analyzed multinational sales data, revealing an overall increase in gabapentinoid consumption across 65 countries and regions from 2008 to 2018.
Celadrin is an over-the-counter medication marketed as a topical analgesic. It is a cream that is used for muscle and joint pains including osteoarthritis , strains, bruises, and sprains. [ 1 ] The active ingredient is menthol [ 2 ] and it also contains cetylated and esterified fatty acids .
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