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Serious side effects may include liver problems or Clostridioides difficile associated diarrhea. [3] It is unclear if use during pregnancy is safe. [3] Rifapentine is in the rifamycin family of medication and works by blocking DNA-dependent RNA polymerase. [3] Rifapentine was approved for medical use in the United States in 1998. [2]
Common side effects include nausea, vomiting, diarrhea, and loss of appetite. [3] It often turns urine, sweat, and tears a red or orange color. [3] Liver problems or allergic reactions may occur. [3] It is part of the recommended treatment of active tuberculosis during pregnancy, though its safety in pregnancy is not known. [3]
In addition, rifabutin and rifapentine have both been used against tuberculosis acquired in HIV-positive patients. Although Tuberculosis therapy remains the most important use of Rifampin, an increasing problem with serious Multiple Drug Resistant bacterial infections has led to some use of antibiotic combinations containing Rifampin to treat them.
Side effects are those of the underlying medications. [1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired. [3] More severe side effects include liver problems. [3] Use is generally not recommended in children. [1] It is unclear if use is safe in pregnancy. [4]
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Side effects are those of the underlying medications. [1] Use may not be suitable in children. [1] It is on the World Health Organization's List of Essential ...
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Side effects are those of the underlying medications. [1] Pyridoxine may be used to decrease the risk of numbness. [2] It is not recommended in people with liver problems or severe kidney problems. [3] Use may not be suitable in children. [1] It is unclear if use during pregnancy is safe. [3]
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