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Warfarin, sold under the brand name Coumadin among others, is an anticoagulant medication. [12] While the drug is described as a "blood thinner", it does not reduce viscosity but rather prevents blood clots ( thrombus ) from forming ( coagulating ).
Direct factor Xa inhibitors can be considered as an alternative to warfarin, particularly if a person is on several other medications that interact with warfarin, or if attending medical appointments and laboratory monitoring becomes difficult. [8]
There are three types of DTIs, dependent on their interaction with the thrombin molecule. Bivalent DTIs (hirudin and analogs) bind both to the active site and exosite 1, while univalent DTIs bind only to the active site. [1] The third class of inhibitors, which are gaining importance recently, is the allosteric inhibitors.
Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.In the majority of circumstances, drugs have 3 types of names: chemical names, the most important of which is the IUPAC name; generic or nonproprietary names, the most important of which are international nonproprietary names (INNs); and trade names, which are brand names. [1]
All proton pump inhibitors except for rabeprazole and pantoprazole are metabolized by the hepatic CYP450 enzyme and therefore, may interact with the metabolism of clopidogrel. Omeprazole is considered to have higher potential for drug-drug interaction than other protein pump inhibitors because it is a CYP2C19 inhibitor. [17]
Escitalopram can interact with a variety of medications, including both over-the-counter medications and prescription drugs. It’s also possible for escitalopram to interact with certain ...
The following drugs can have negative interactions with rosuvastatin and should be discussed with the prescribing doctor: [14] [4] Coumadin anticoagulants ('blood thinners', e.g. warfarin) can affect the removal of rosuvastatin; Ciclosporin, colchicine
Compared to warfarin it has fewer interactions with other medications. [13] It is a direct factor Xa inhibitor. [9] In 2007, Pfizer and Bristol-Myers Squibb began the development of apixaban as an anticoagulant. [14] Apixaban was approved for medical use in the European Union in May 2011, and in the United States in December 2012.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261