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For example, actin, the ATPase domain of the heat shock protein, and hexokinase together form a superfamily. Fold (major structural similarity): Proteins are defined as having a common fold if they have the same major secondary structures in the same arrangement and with the same topological connections.
In structural geology, a syncline is a fold with younger layers closer to the center of the structure, whereas an anticline is the inverse of a syncline. A synclinorium (plural synclinoriums or synclinoria ) is a large syncline with superimposed smaller folds. [ 1 ]
When the limbs of a fold converge upward, the fold is referred to as an antiform. Conversely, when the limbs of a fold converge downward, the fold is known as a synform. Not to be confused with these terms (antiform and synform), the terms anticline and syncline are used in the description of the stratigraphic significance of the fold.
If the angle between the limbs is large (70–120 degrees), then the fold is an "open" fold, but if the angle between the limbs is small (30 degrees or less), then the fold is a "tight" fold. [4] If an anticline plunges (i.e., the anticline crest is inclined to the Earth's surface), it will form V s on a geologic map view that point in the ...
The definition of disharmonic folds (below) however, incorporates many types of symmetric folds over a larger area encompassing many geometries and attributes of the basic models and may be better suited to the application of these models. Figure 3. Disharmonic folding of a detachment fold using a symmetric geometric fold as a model.
This type of method is also known as 3D-1D fold recognition due to its compatibility analysis between three-dimensional structures and linear protein sequences. This method has also given rise to methods performing an inverse folding search by evaluating the compatibility of a given structure with a large database of sequences, thus predicting ...
This method does therefore require a velocity model, making it resource-intensive because building a seismic velocity model is a long and iterative process. The significant advantage to this migration method is that it can be successfully used in areas with lateral velocity variations, which tend to be the areas that are most interesting to ...
The folding funnel hypothesis is closely related to the hydrophobic collapse hypothesis, under which the driving force for protein folding is the stabilization associated with the sequestration of hydrophobic amino acid side chains in the interior of the folded protein. This allows the water solvent to maximize its entropy, lowering the total ...