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Citric acid also dissolves in absolute (anhydrous) ethanol (76 parts of citric acid per 100 parts of ethanol) at 15 °C. It decomposes with loss of carbon dioxide above about 175 °C. Citric acid is a triprotic acid , with pK a values, extrapolated to zero ionic strength, of 3.128, 4.761, and 6.396 at 25 °C. [ 21 ]
More than 1,100 monographs, which include chemical formula and structure, chemical weight, function, definition, packaging and storage, labelling requirements, test procedures and more. Fourteen appendices, which detail more than 150 tests and assays , with step-by-step guidance for the analysis of enzymes , impurities such as metals and ...
Acid-citrate-dextrose or acid-citrate-dextrose solution, also known as anticoagulant-citrate-dextrose or anticoagulant-citrate-dextrose solution (and often styled without the hyphens between the coordinate terms, thus acid citrate dextrose or ACD) is any solution of citric acid, sodium citrate, and dextrose in water.
McIlvaine buffer is a buffer solution composed of citric acid and disodium hydrogen phosphate, also known as citrate-phosphate buffer.It was introduced in 1921 by the United States agronomist Theodore Clinton McIlvaine (1875–1959) from West Virginia University, and it can be prepared in pH 2.2 to 8 by mixing two stock solutions.
Toxicity characteristic leaching procedure (TCLP) is a soil sample extraction method for chemical analysis employed as an analytical method to simulate leaching through a landfill. The testing methodology is used to determine if a waste is characteristically hazardous, i.e., classified as one of the "D" listed wastes by the U.S. Environmental ...
Monosodium citrate, more correctly, sodium dihydrogen citrate (Latin: natrium citricum acidulatum), is an acid salt of citric acid. Disodium citrate and trisodium citrate are also known. It can be prepared by partial neutralisation of citric acid [3] with an aqueous solution of sodium bicarbonate or carbonate. It has a slightly acidic taste. [3]
The fixed-dose procedure (FDP), proposed in 1992 by the British Toxicology Society, is a method to assess a substance's acute oral toxicity. [ 1 ] [ 2 ] In comparison to the older LD 50 test developed in 1927, this procedure produces similar results while using fewer animals and causing less pain and suffering. [ 3 ]
[28] [29] One such criteria is the parameter "Q", which is a percentage value denoting the quantity of dissolved active ingredient within the monograph of a sample solution. If the initial sample analysis, known as S1 or stage 1 testing fails to meet the acceptable value for Q, then additional testing known as stage 2 and 3 testing is required.