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Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis, [1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature. [2]
Methyldichlorophosphine belongs to the group of halophosphines, some of which are used as intermediates in the production of plant protection agents, stabilizers for plastics, and catalysts.
[2] Dimethyl methylphosphonate is a schedule 2 chemical as it may be used in the production of chemical weapons. It will react with thionyl chloride to produce methylphosphonic acid dichloride, which is used in the production of sarin and soman nerve agents. Various amines can be used to catalyse this process. [3]
Methylphosphonic acid is an organophosphorus compound with the chemical formula CH 3 P(O)(OH) 2. The phosphorus center is tetrahedral and is bonded to a methyl group, two OH groups and an oxygen. Methylphosphonic acid is a white, non-volatile solid that is poorly soluble in organic solvent but soluble in water and common alcohols. [2]
3.15 mg/kg (mice, subcutaneous) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references
Methylphosphine is the simplest organophosphorus compound with the formula CH 3 PH 2, often written MePH 2. It is a malodorous gas that condenses to a colorless liquid. It can be produced by methylation of phosphanide salts: [1] KPH 2 + MeI → MePH 2 + KI
Octenidine dihydrochloride is active against Gram-positive and Gram-negative bacteria. [5]In vitro suspension tests with 5 minute exposure time have shown that octenidine requires lower effective concentrations than chlorhexidine to kill common bacteria like Staphylococcus aureus, Escherichia coli, Proteus mirabilis and the yeast Candida albicans.
Titanocene dichloride is known to be a potential anticancer drug [2] since the late 1970s. After initial clinical trials against breast and renal-cell cancer were performed with this compound, [3] [4] the search for improved derivatives started. [5]