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A particular interest in oat β-glucan arose after a cholesterol lowering effect from oat bran reported in 1981. [2] In 1997, the FDA approved of a claim that intake of at least 3.0 g of β-glucan from oats per day decreased absorption of dietary cholesterol and reduced the risk of coronary heart disease. The approved health claim was later ...
A 2021 meta-analysis of clinical trials concluded that oat beta-glucan with molecular weights greater than 300 kg/mol reduced incremental area-under-the-curve by 23%, peak blood glucose by 28%, and insulin by 22% in a dose-responsive fashion, with similar results in participants with or without diabetes. [24]
As discussed in FDA regulation 21 CFR 101.81, the daily dietary intake levels of soluble fiber from sources listed above associated with reduced risk of coronary heart disease are: 3 g or more per day of beta-glucan soluble fiber from either whole oats or barley, or a combination of whole oats and barley
As a rich source of dietary fiber (10 grams per 100 gram serving), whole oats supply beta-glucan (4 grams per 100 gram serving; table), a soluble fiber with cholesterol-lowering effects. [ 3 ] [ 6 ] [ 7 ]
A glucan is a polysaccharide derived from D-glucose, [1] linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Glucans are noted in two forms: alpha glucans and beta glucans.
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, beta6-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase, core 2 acetylglucosaminyltransferase, core 6-beta-GlcNAc-transferase A, UDP-N-acetyl-D-glucosamine ...
This theory also coincides with that of other beta-glucans. High doses of schizophyllan are not the primary determinant of an immunological response. Studies have validated that 10 mg (or less) of a high quality, adequately processed chemically similar beta-glucan is a sufficient dose to elicit a measurable effect on immune cells.
Mixed-linkage glucan (MLG), sometimes incorrectly referred to as beta-glucan, is a hemicellulosic polysaccharide consisting of β-D(1-3) and β-D(1-4) linked glucosyl residues. MLG is highly prevalent within the Poales , where it has important properties in the diet .
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