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In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...
Tends to produce less extrapyramidal side effects than typical antipsychotics but more extrapyramidal side effects than sertindole, clozapine and quetiapine. [9] [10] Mild and transient constipation and xerostomia (dry mouth) [citation needed] Dizziness [citation needed] Weight gain of over 15% of one's initial body weight.
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The authors noted an apparent superior efficacy of olanzapine to the other drugs in terms of reduction in psychopathology and rate of hospitalizations, but olanzapine was associated with relatively severe metabolic effects such as a major weight gain problem (averaging 9.4 lbs over 18 months) and increases in glucose, cholesterol, and ...
Extrapyramidal side effects, although potentially serious, are infrequent to rare from olanzapine, [43] but may include tremors and muscle rigidity. Aripiprazole, asenapine, clozapine, quetiapine and olanzapine, in comparison to other antipsychotic drugs, are less frequently associated with hyperprolactinaemia. Although these drugs can cause ...
[63] [64] Aripiprazole, quetiapine extended-release, and olanzapine (when used in conjunction with fluoxetine) have received the Food and Drug Administration (FDA) labelling for this indication. [65] There is, however, a greater risk of side effects with their use compared to using traditional antidepressants. [63]
Image source: Getty Images. 1. Cost increases for Parts A and B. Original Medicare's premiums and deductibles went up in 2025. The Part A annual deductible increased from $1,632 to $1,676, and the ...
People on typical antipsychotics tend to have a higher rate of extrapyramidal side effects while some atypicals are associated with considerable weight gain, diabetes, and risk of metabolic syndrome; this is most pronounced with olanzapine, while risperidone and quetiapine are also associated with weight gain. [9]
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