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Patients present with an acute onset of swelling, pain, erythema, prominent tenderness, warmness and limited range of motion in both ankles. [1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension.
Lymphedema can also be categorized by its severity (usually compared to a healthy extremity): [46] Grade 1 (mild edema): Involves the distal parts such as a forearm and hand or a lower leg and foot. The difference in circumference is less than 4 cm (1.6 in) and no other tissue changes are present.
Compartment syndrome usually presents within a few hours of an inciting event, but may present anytime up to 48 hours after. [9] The limb affected by compartment syndrome is often associated with a firm, wooden feeling or a deep palpation, and is usually described as feeling tight.
Podoconiosis causes bilateral yet asymmetrical leg swelling with overlying firm nodules. Early on, symptoms may include itching, tingling, widening of the forefoot, and swelling which then progress to soft edema, skin fibrosis, papillomatosis, and nodule formation resembling moss, giving rise to the disease's alternate name of "mossy foot" in some regions of the world. [3]
Rest pain is a continuous burning pain of the lower leg or feet. It begins, or is aggravated, after reclining or elevating the limb and is relieved by sitting or standing. It is more severe than intermittent claudication, which is also a pain in the legs from arterial insufficiency. [citation needed]
Acute limb ischaemia (ALI) occurs when there is a sudden lack of blood flow to a limb [1] within 14 days of symptoms onset. [2] On the other hand, when the symptoms exceed 14 days, [3] it is called critical limb ischemia (CLI).
As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs. If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. [3]
The mean size of an inguinal lymph node, as measured over the short-axis, is approximately 5.4 mm (range 2.1-13.6 mm), with two standard deviations above the mean being 8.8 mm. [5] A size of up to 10 mm is generally regarded as a cut-off value for normal vs abnormal inguinal lymph node size.
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