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The name "pyogenic granuloma" is misleading, as it is neither pyogenic or a true granuloma. Rather, it is a capillary hemangioma of lobular subtype, which is why such a lesion is prone to bleeding. [5] It is also not truly pyogenic (pus-producing), as the cause is hormonal or traumatic and has no association with infection or pus production.
Neoplasms of the nailbed may often present with paronychia, ingrown nail, onycholysis, pyogenic granuloma, nail-plate dystrophy, longitudinal erythronychia, bleeding, and discolorations. [ 1 ] : 792 There are various benign and malignant neoplasms that may occur in or overlying the nail matrix and in the nailbed, and symptoms may include pain ...
Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
Example of hypergranulation tissue from a cut on a finger. During the migratory phase of wound healing, granulation tissue is: light red or dark pink, being perfused with new capillary loops or "buds"; soft to the touch; moist; bumpy (granular) in appearance, due to punctate hemorrhages; pulsatile on palpation; painless when healthy; [2]
PAPA syndrome is inherited in an autosomal dominant fashion, which means that if one parent is affected, there is a 100% chance that a child will inherit the disease from a homozygous affected parent and a 50% chance that a child will inherit the disease from an affected heterozygous parent.
English: Histopathology of pyogenic granuloma - high magnification. HE stain. Annotated are major features: Endothelial cell clusters, inflammation, variable amount of mitoses, and edema. - Christopher S. Hale, M.D.. Skin nonmelanocytic tumor - Vascular tumors - Capillary / pyogenic granuloma. PathologyOultines. Topic Completed: 1 August 2012.
They usually occur in the elderly population (mean age 65.1–66.6 in different studies) as small (<2 centimeters), solitary dome-shaped papules, plaques, or nodules, that are skin-colored, pink, red, white, or blue and range from smooth to wart-like, ulcerative, [4] or pyogenic granuloma-like lesions. [10]
When surgical removal of the granuloma is not applicable due to size or location, the lesions have been found to respond well to radiation therapy as well as glucocorticoids or steroids. [3] While recurrence rate for plasma cell granulomas is very low, they have been reported; therefore, it is recommended that patients come back for yearly ...