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  2. Radiation damage - Wikipedia

    en.wikipedia.org/wiki/Radiation_damage

    Exposure to radiation causes chemical changes in gases. The least susceptible to damage are noble gases, where the major concern is the nuclear transmutation with follow-up chemical reactions of the nuclear reaction products. High-intensity ionizing radiation in air can produce a visible ionized air glow of telltale

  3. Radiation-induced cancer - Wikipedia

    en.wikipedia.org/wiki/Radiation-induced_cancer

    Radiation hormesis is the conjecture that a low level of ionizing radiation (i.e., near the level of Earth's natural background radiation) helps "immunize" cells against DNA damage from other causes (such as free radicals or larger doses of ionizing radiation), and decreases the risk of cancer. The theory proposes that such low levels activate ...

  4. Free radical damage to DNA - Wikipedia

    en.wikipedia.org/wiki/Free_radical_damage_to_DNA

    Radiolysis of intracellular water by ionizing radiation creates peroxides, which are relatively stable precursors to hydroxyl radicals. 60%–70% of cellular DNA damage is caused by hydroxyl radicals, [3] yet hydroxyl radicals are so reactive that they can only diffuse one or two molecular diameters before reacting with cellular components.

  5. DNA repair - Wikipedia

    en.wikipedia.org/wiki/DNA_repair

    In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. [2] Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the ...

  6. Acute radiation syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_radiation_syndrome

    The human body contains many types of cells and a human can be killed by the loss of a single type of cells in a vital organ. For many short term radiation deaths (3–30 days), the loss of two important types of cells that are constantly being regenerated causes death.

  7. Biological effects of radiation on the epigenome - Wikipedia

    en.wikipedia.org/wiki/Biological_effects_of...

    Radiation exposure through ionizing radiation (IR) affects a variety of processes inside of an exposed cell. IR can cause changes in gene expression, disruption of cell cycle arrest, and apoptotic cell death. The extent of how radiation effects cells depends on the type of cell and the dosage of the radiation.

  8. Free-radical theory of aging - Wikipedia

    en.wikipedia.org/wiki/Free-radical_theory_of_aging

    Oxidative free radicals, such as the hydroxyl radical and the superoxide radical, can cause DNA damages, and such damages have been proposed to play a key role in the aging of crucial tissues. [20] DNA damage can result in reduced gene expression, cell death and ultimately tissue dysfunction. [20]

  9. Mutation - Wikipedia

    en.wikipedia.org/wiki/Mutation

    These types of mutations are usually prompted by environmental causes, such as ultraviolet radiation or any exposure to certain harmful chemicals, and can cause diseases including cancer. [ 91 ] With plants, some somatic mutations can be propagated without the need for seed production, for example, by grafting and stem cuttings.