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The DNA Learning Center (DNALC) is a genetics learning center affiliated with the Cold Spring Harbor Laboratory, in Cold Spring Harbor, New York.It is the world's first science center devoted entirely to genetics education and offers online education, class field trips, student summer day camps, and teacher training.
Cold Spring Harbor Laboratory It is located in Laurel Hollow on Long Island , New York. It is one of 68 institutions supported by the Cancer Centers Program of the U.S. National Cancer Institute (NCI) and has been an NCI-designated Cancer Center since 1987. [ 3 ]
Cold Spring Harbor Protocols (formerly CSH Protocols) is an online scientific journal and methods database for biologists, published by Cold Spring Harbor Laboratory Press. Protocols are presented step-by-step and edited in the style that has made Molecular Cloning, Antibodies, Cells and many other CSH manuals essential [ tone ] to the work of ...
While an assistant professor of Biochemistry and Molecular Biology at Harvard, and a member of the Cold Spring Harbor Laboratory (CSHL) faculty, Maniatis collaborated with Drs. Fotis Kafatos and Argiris Efstratiadis to develop a method for synthesizing and cloning full length double stranded DNA copies of messenger RNA (termed “copy” or cDNA).
Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine. [2]
Sambrook is best known for his studies on DNA tumor viruses and the molecular biology of normal and neoplastic cells.His Tumour Virus Group at Cold Spring Harbor identified and mapped all of the major genes of adenoviruses and SV40, determined their transcriptional control in infected and transformed cells, and elucidated the mechanism of integration of these viruses into the genome of the ...
Several DNA polymerases have been described with distinct properties that define their specific utilisation in a PCR, in real-time PCR or in an isothermal amplification. Being DNA polymerases, the thermostable DNA polymerases all have a 5'→3' polymerase activity, and either a 5'→3' or a 3'→5' exonuclease activity.
From 1992-1997 he was a director of informatics at the Massachusetts Institute of Technology (MIT) Genome Centre, Whitehead Institute of Biomedical Research. From 1998 to 2004 he was an associate professor at Cold Spring Harbor Laboratory.