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Cerebellar abiotrophy (CA), also called cerebellar cortical abiotrophy (CCA), is a genetic neurological disease in animals, best known to affect certain breeds of horses, dogs and cats. It can also develop in humans. It develops when the neurons known as Purkinje cells, located in the cerebellum of the brain, begin to die off. These cells ...
Osteoarthritis is a degenerative disease marked by the breakdown of cartilage between joints resulting in painful bone-to-bone contact. [4] The underlying deformity of the joint may get worse over time, or may remain static. A dog may have good radiographs and yet be in pain, or may have very poor radiographs and have no apparent pain issues.
A chromosome has been located in dogs that confers a high risk of susceptibility to OCD. [21] Canine chromosome 7 has been found to be most significantly associated with obsessive compulsive disorder in dogs, or more specifically, canine compulsive disorder (CCD). This breakthrough helped further relate OCD in humans to CCD in canines.
Naked foal syndrome (NFS) is a genetic disorder specific to the Akhal-Teke horse breed. A rare genodermatosis, it is characterized by almost complete hairlessness and mild ichthyosis. The condition is inherited as a monogenic autosomal recessive trait, and affected horses typically die between a few weeks and three years of age. The exact cause ...
In most cases the cause is unknown. However, in dogs and cats it is thought to be most likely related to in utero viral infections, toxins or genetic disorders. [14] Other possible causes, if they occurred during the development period of the cerebellum and inhibit its growth, include: [15] hypoxia
Mastocytomas in dogs occur mainly in the skin and subcutaneous tissue. Very rarely, they are found in internal organs such as the small intestine, [5] the mucosa of the mouth, [6] the nasal mucosa [7] or the conjunctiva. [8] About 20% of all skin tumors [9] and 6% of all tumors [10] in dogs are mastocytomas.
Dog cells normally have 78 chromosomes, while the cancer cells contain 57–64 chromosomes [9] that are very different in appearance from normal dog chromosomes. All dog chromosomes except X and Y are acrocentric, having a centromere very near to the end of the chromosome, while many of the CTVT chromosomes are metacentric or submetacentric ...
Chromosome 7 is one of the 23 pairs of chromosomes in humans, who normally have two copies of this chromosome. Chromosome 7 spans about 160 million [ 4 ] base pairs (the building material of DNA ) and represents between 5 and 5.5 percent of the total DNA in cells .