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Since these drugs may cause paralysis of the diaphragm, mechanical ventilation should be at hand to provide respiration. In addition, these drugs may exhibit cardiovascular effects, since they are not fully selective for the nicotinic receptor and hence may have effects on muscarinic receptors . [ 11 ]
This causes prolonged stimulation and desensitization of neuroreceptors, causing skeletal muscle relaxation effects such as paralysis. [1] Depolarizing neuromuscular blockers, notably succinylcholine, tend to be preferred over non-depolarizing neuromuscular blockers due to their long-acting and rapid-onset properties.
Flaccid paralysis resulting from cholinergic crisis can be distinguished from myasthenia gravis by the use of the drug edrophonium (Tensilon), as it only worsens the paralysis caused by cholinergic crisis but strengthens the muscle response in the case of myasthenia gravis. Edrophonium is a cholinesterase inhibitor, hence it increases the ...
Most people know that GLP-1 receptor agonist medications like Ozempic and Wegovy can cause relatively minor ... sleep issues, stomach cramps, pancreatitis, and gastroparesis (i.e. stomach paralysis).
Some reports say Ozempic and Mounjaro cause gastroparesis—but clinical trials do not. Doctors explain a potential link between weight loss drugs and stomach paralysis.
They are often used during surgical procedures and in intensive care and emergency medicine to cause temporary paralysis. Spasmolytics, also known as "centrally acting" muscle relaxant, are used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions.
Combined use of medications with anticholinergics may cause synergistic (supra-additive), additive, or antagonistic interactions, leading to no therapeutic effect or overdosing. [25] [26] Below listed are some medications or food that can interact with anticholinergics. Medications indicated for: Irregular heartbeat, e.g. disopyramide ...
Drugs that interfere with nerve function, such as curare, can also cause paralysis. Pseudoparalysis ( pseudo- meaning "false, not genuine", from Greek ψεῦδος [ 7 ] ) is voluntary restriction or inhibition of motion because of pain, incoordination, orgasm, or other cause, and is not due to actual muscular paralysis. [ 8 ]