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HIVE Logo. The High-performance Integrated Virtual Environment (HIVE) is a distributed computing environment used for healthcare-IT and biological research, including analysis of Next Generation Sequencing (NGS) data, preclinical, clinical and post market data, adverse events, metagenomic data, etc. [1] Currently it is supported and continuously developed by US Food and Drug Administration ...
High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [ 2 ] [ 3 ] Using robotics , data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to ...
Virtual screening (VS) is a computational technique used in drug discovery to search libraries of small molecules in order to identify those structures which are most likely to bind to a drug target, typically a protein receptor or enzyme. [2] [3] Virtual screening has been defined as "automatically evaluating very large libraries of compounds ...
This would send the simulated virtual person with diabetes ('Joy Wilson' [pseudonym]) markedly hyperglycemic in the afternoon (with a predicted blood glucose level of 18.8 mmol/L [338 mg/dL] at 2:30pm) — and leave her at significant risk of developing diabetic ketoacidosis. The simulated blood glucose profile is shown in the upper graph, and ...
Classical High throughput screening robotics are now being tied closer to cell biology, principally using technologies such as High-content screening.High throughput cell biology dictates methods that can take routine cell biology from low scale research to the speed and scale necessary to investigate complex systems, achieve high sample size, or efficiently screen through a collection.
The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
Telehealth is sometimes discussed interchangeably with telemedicine, the latter being more common than the former. The Health Resources and Services Administration distinguishes telehealth from telemedicine in its scope, defining telemedicine only as describing remote clinical services, such as diagnosis and monitoring, while telehealth includes preventative, promotive, and curative care ...
MDSi has a field team of health professionals, which travels to remote and rural communities in Alberta, particularly off-reserve Aboriginal Communities (including the eight incorporated Métis Settlements in Alberta) to carry out diabetes and cardiovascular screening. Little is known about diabetes and Métis people. MDSi is collecting the ...