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Whipple's disease is a rare systemic infectious disease caused by the bacterium Tropheryma whipplei.First described by George Hoyt Whipple in 1907 and commonly considered as a gastrointestinal disorder, Whipple's disease primarily causes malabsorption, but may affect any part of the human body, including the heart, brain, joints, skin, lungs and the eyes. [1]
The pain persists for at least three months. Enthesitis of the manubriocostal, costosternal, and costovertebral articulations causes thoracic pain. It worsens with coughing and deep inspirations, and it restricts the expansion of the respiratory system with varying-length episodes. Ankylosing spondylitis has been linked with dactylitis.
Whipple's triad is a collection of three signs (called Whipple's criteria) that suggests that a patient's symptoms result from hypoglycaemia that may indicate insulinoma. The essential conditions are symptoms of hypoglycaemia, low blood plasma glucose concentration , and relief of symptoms when plasma glucose concentration is increased.
Whipple's Triad: Hypoglycaemia during attacks, resolution of symptoms upon correction of blood glucose, symptoms brought about by low glucose states. Insulinoma: Triad of Aortic stenosis: Chest pain, Heart failure, Syncope: Aortic stenosis: Murphy's triad: Pain-> Vomiting -> Fever: Acute appendicitis: Tillaux's triad
[3] [4] Chronic pain is considered a syndrome because of the associated symptoms that develop in those experiencing this disorder. [5] Chronic pain affects approximately 20% of people worldwide and accounts for 15–20% of visits to a physician. [3] Pain can be categorized according to its location, cause, or the anatomical system which it affects.
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Pernicious anemia may be present without a person experiencing symptoms at first, over time, feeling tired and weak, lightheadedness, dizziness, headaches, rapid or irregular heartbeat, breathlessness, glossitis (a sore red tongue), poor ability to exercise, low blood pressure, cold hands and feet, pale or yellow skin, easy bruising and ...
epigastric pain with pressure on McBurney's point Abadie's sign: Jean Marie Charles Abadie: endocrinology: Graves' disease: levator palpebrae superioris spasm Abadie's symptom: Joseph Louis Irenée Jean Abadie: neurology: tabes dorsalis: absence of pain on Achilles tendon pressure Abderhalden reaction: Emil Abderhalden: obstetrics: pregnancy ...