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In humans, the CCR5 gene that encodes the CCR5 protein is located on the short (p) arm at position 21 on chromosome 3. Certain populations have inherited the Delta 32 mutation, resulting in the genetic deletion of a portion of the CCR5 gene. Homozygous carriers of this mutation are resistant to infection by macrophage-tropic (M-tropic) strains ...
Yersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both Yersinia enterocolitica and Yersinia pseudotuberculosis, the pathogen from which Y. pestis evolved [1] [2] and responsible for the Far East scarlet-like fever.
Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]
There are two main forms of plague infection: bubonic, which is caused by a flea bite or blood contact with another infected animal or material and is characterized by swollen lymph nodes or ...
Operation PX (Japanese: PX作戦, romanized: PX Sakusen), also known as Operation Cherry Blossoms at Night (夜桜作戦 Yozakura Sakusen) [1] was a planned Japanese military attack on civilians in the United States using biological weapons, devised during World War II.
This is an accepted version of this page This is the latest accepted revision, reviewed on 28 February 2025. Disease caused by Yersinia pestis bacterium This article is about the disease caused by Yersinia pestis. For other uses, see Plague. Medical condition Plague Yersinia pestis seen at 200× magnification with a fluorescent label. Specialty Infectious disease Symptoms Fever, weakness ...
A theory put forth by Stephen O'Brien is that the Black Death is likely responsible by natural selection for the high frequency of the CCR5-Δ32 genetic defect in people of European descent. The gene affects T cell function and provides protection against HIV , smallpox and possibly plague, [ 51 ] but for the last, no explanation exists on how ...
“Our genome today is a reflection of our whole evolutionary history" as we adapt to different germs, said Luis Barreiro, a senior author of the research. The Black Death in the 14th century was ...