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Gene structure is the organisation of specialised sequence elements within a gene.Genes contain most of the information necessary for living cells to survive and reproduce. [1] [2] In most organisms, genes are made of DNA, where the particular DNA sequence determines the function of the gene.
A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor (i.e. regulatory protein).Structural genes are typically viewed as those containing sequences of DNA corresponding to the amino acids of a protein that will be produced, as long as said protein does not function to regulate gene expression.
A derived G-allele point mutation with pleiotropic effects in EDAR, 370A or rs3827760, is found in ancient and modern East Asians, North Asians, Southeast Asians, Nepalese, [5] and Native Americans but not common in African or European populations.
The words cistron and gene were coined before the advancing state of biology made it clear to many people that the concepts they refer to, at least in some senses of the word gene, are either equivalent or nearly so. The same historical naming practices are responsible for many of the synonyms in the life sciences.
p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers.