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Later studies made it apparent connexins could connect directly to the cell exterior meaning they are a conduit for the release an uptake of signalling molecules from the environment external to the cell. [11] Furthermore, pannexins appear to do this to such an extent they may rarely if ever participate in direct cell to cell coupling. [12]
The carboxy-terminal domain of RNA polymerase II typically consists of up to 52 repeats of the sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. [32] The domain stretches from the core of the RNAPII enzyme to the exit channel, this placement is effective due to its inductions of "RNA processing reactions, through direct or indirect interactions with ...
Direct realism, also known as naïve realism, argues we perceive the world directly. In the philosophy of perception and philosophy of mind, direct or naïve realism, as opposed to indirect or representational realism, are differing models that describe the nature of conscious experiences; [1] [2] out of the metaphysical question of whether the world we see around us is the real world itself ...
Direct reciprocity was proposed by Robert Trivers as a mechanism for the evolution of cooperation. [1] If there are repeated encounters between the same two players in an evolutionary game in which each of them can choose either to "cooperate" or "defect", then a strategy of mutual cooperation may be favoured even if it pays each player, in the short term, to defect when the other cooperates.
In the direct pathway, the motor cortices send activating signals to the caudate and putamen (which together form the dorsal striatum). The cells of the direct pathway in the caudate and putamen that receive these signals are inhibitory and, once they become activated, send inhibitory signals to the GPi and SNpr and stop activity there.
The theory is based on the hypothesis that cooperation helps in transmitting underlying genes to future generations either through increasing the reproductive successes of the individual (direct fitness) or of other individuals who carry the same genes (indirect fitness). Direct benefits can result from simple by-product of cooperation or ...
The indirect pathway, sometimes known as the indirect pathway of movement, is a neuronal circuit through the basal ganglia and several associated nuclei within the central nervous system (CNS) which helps to prevent unwanted muscle contractions from competing with voluntary movements. [1] It operates in conjunction with the direct pathway.
Allospecific T lymphocytes may be stimulated by three major pathways: direct recognition, indirect recognition or semidirect recognition. The pathway involved in specific cases is dictated by intrinsic and extrinsic factors of allograft and directly influence nature and magnitude of T lymphocytes mediated immune response.