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Diagnosis relies on finding the eggs or the adult pinworms. [19] Individual eggs are invisible to the naked eye, but they can be seen using a low-power microscope. [21] On the other hand, the light-yellowish thread-like adult pinworms are clearly visually detectable, usually during the night when they move near the anus, or on toilet paper.
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. [2] It is taken by mouth. [2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash. [2] A lower dose should be used in people with liver disease. [2]
Praziquantel has a serum half-life of 0.8 to 1.5 hours in adults with normal renal and liver function. Metabolites have a half-life of 4 to 5 hours. In patients with significantly impaired liver function ( Child-Pugh score B and C), the serum half-life is increased to 3 to 8 hours.
This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent. [6] [7] It is taken by mouth. [5] Mebendazole is usually well tolerated. [5] Common side effects include headache, vomiting, and ringing in the ...
Pyrvinium (Viprynium) is an anthelmintic effective for pinworms. [1] Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. [2] [3] Pyrvinium was identified as a potent Wnt inhibitor, acting through activation of Casein kinase CK1α. [4] [5]
Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]
The estimations of the number of eggs in a gravid female pinworm range from about 11,000 [19] to 16,000. [21] The egg-laying process begins about five weeks after initial ingestion of pinworm eggs by the human host. [19] The gravid female pinworms migrate through the colon towards the rectum at a rate of 12 to 14 cm per hour. [19]
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