Search results
Results from the WOW.Com Content Network
[1] [2] Once stained as part of a sample, these organisms can resist the acid and/or ethanol-based decolorization procedures common in many staining protocols, hence the name acid-fast. [2] The mechanisms of acid-fastness vary by species although the most well-known example is in the genus Mycobacterium, which includes the species responsible ...
M. marinum and perhaps M. bovis have been shown to sporulate; [9] however, this has been contested by further research. [10] The distinguishing characteristic of all Mycobacterium species is a thick, hydrophobic , and mycolic acid -rich cell wall made of peptidoglycan and arabinogalactan , with these unique components offering targets for new ...
Mycobacterium leprae is an intracellular, pleomorphic, non-sporing, non-motile, acid-fast, pathogenic bacterium. [3] It is an aerobic bacillus (rod-shaped bacterium) with parallel sides and round ends, surrounded by the characteristic waxy coating of mycolic acid unique to mycobacteria .
M. leprae is an aerobic, rod-shaped, acid-fast bacterium with a waxy cell envelope characteristic of the genus Mycobacterium. [34] M. leprae and M. lepromatosis are obligate intracellular pathogens and cannot grow or be cultured outside of host tissues. [5] [35] However, they can be grown using research animals such as mice and armadillos. [36 ...
The Kinyoun method can be modified as a weak acid fast stain, which uses 0.5–1.0% sulfuric acid instead of hydrochloric acid.The weak acid fast stain, in addition to staining Mycobacteria, will also stain organisms that are not able to maintain the carbol fuchsin after decolorizing with HCl, such as Nocardia species and Cryptosporidium.
When looking at the smears for TB, it is stained using an acid-fast stain. These acid-fast organisms like Mycobacterium contain large amounts of lipid substances within their cell walls called mycolic acids. These acids resist staining by ordinary methods such as a Gram stain. [9] It can also be used to stain a few other bacteria, such as Nocardia.
Mycolic acid provides a protective barrier that allows the bacterial cell to resist lysosomal degradation by phagocytic white blood cells. [ 17 ] [ 15 ] This allows the bacteria to act as facultative intracellular parasites once they have been phagocytized; the phagocyte eventually migrates to the lymph node, where chronic infection occurs.
Mycobacterium phlei is a species of acid-fast bacteria in the genus Mycobacterium. [1] It is characterized as one of the fast-growing mycobacteria. M. phlei has only occasionally been isolated in human infections, and patients infected with M. phlei generally respond well to anti-mycobacterial therapy. M. phlei has an unusually high GC-content ...