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Corticosteroids and immunoglobulins are two commonly used treatments for warm antibody AIHA. Initial medical treatment consists of prednisone. If ineffective, splenectomy should be considered. [citation needed] If refractory to both these therapies, other options include rituximab, [4] [5] danazol, cyclosphosphamide, azathioprine, or ...
Hemolytic anemia accounts for 5% of all existing anemias. [2] It has numerous possible consequences, ranging from general symptoms to life-threatening systemic effects. [2] The general classification of hemolytic anemia is either intrinsic or extrinsic. [3] Treatment depends on the type and cause of the hemolytic anemia. [2]
The test was premature and was forgotten. In 1946, Boorman, Dodd, and Loutit applied the direct antiglobulin test to a variety of hemolytic anemias, and laid the foundation for the clear distinction of autoimmune from congenital hemolytic anemia. [citation needed] A hemolytic state exists whenever the red cell survival time is shortened from ...
Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...
An appropriate course of treatment for drug-induced autoimmune hemolytic anemia hasn't yet been established. Once DIIHA has been recognized, the patient must stop whatever drug caused the anemia in order to provide proper treatment. Patients should be given blood transfusions as needed.
Mixed autoimmune hemolytic anemia (MAIHA) is a type of autoimmune hemolytic anemia which combines the features of cold sensitive antibody-induced diseases and warm autoimmune hemolytic anemia. The work-up for diagnosis is complex and the condition can be over-diagnosed. [1] [2] [better source needed]
Its overall phenotype resembles a combination of autoimmune hemolytic anemia and immune thrombocytopenic purpura. [1] [4] [5] Autoimmune hemolytic anemia is a condition in which the red blood cells that normally carry oxygen are destroyed by an autoimmune process. Immune thrombocytopenic purpura is a condition in which platelets are destroyed ...
Hexokinase deficiency manifests is associated with chronic nonspherocytic hemolytic anemia. [3] Hemolytic anemia seems to be the only clinical sign of hexokinase deficiency. [ 4 ] In 1967 the first case of hexokinase deficiency was described by Valentine et al, [ 5 ] since then, less than 50 cases have been reported.
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