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Tolnaftate [1], sold under the brand name TAGRID, among others, is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, liquid, and liquid aerosol . [ 2 ]
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Alkylation of imidazole (2) with bromoketone (1) prepared from o,p-dichloroacetophenone affords the displacement product (3). Reduction of the ketone with sodium borohydride gives the corresponding alcohol ( 4 ).
Triamcinolone acetonide, also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, is a synthetic halogenated cyclic ketal pregnane corticosteroid. [27] It is the C16α,17α acetonide of triamcinolone. [27]
After application to the skin, miconazole can be measured in the skin for up to four days, but less than 1% is absorbed into the bloodstream. When applied to the oral mucosa (and possibly also for vaginal use [9]), it is significantly absorbed. In the bloodstream, 88.2% are bound to plasma proteins and 10.6% to blood cells.
Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. [2] It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. [2]
Bifonazole (trade name Canespor among others [1]) is an imidazole antifungal drug used in form of ointments. It was patented in 1974 and approved for medical use in 1983. [ 2 ] There are also combinations with carbamide for the treatment of onychomycosis .
Tioconazole ointments serve to treat women's vaginal yeast infections. [1] They are available in one day doses, as opposed to the 7-day treatments commonly used in the past. Tioconazole topical (skin) preparations are also available for ringworm , jock itch , athlete's foot , and tinea versicolor or "sun fungus".
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