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Glycolic acid is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization. It is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA ).
Polyglycolide or poly (glycolic acid) (PGA), also spelled as polyglycolic acid, is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. PGA has been known since 1954 as a tough fiber -forming polymer.
One common synthesis route involves the hydrolysis of α-halocarboxylic acids, readily available precursors, to produce 2-hydroxycarboxylic acids. For instance, the production of glycolic acid typically follows this method, utilizing a base-induced reaction, followed by acid workup.
Thioglycolic acid (TGA) is the organic compound HSCH 2 CO 2 H. TGA is often called mercaptoacetic acid (MAA). It contains both a thiol (mercaptan) and carboxylic acid functional groups. It is a colorless liquid with a strongly unpleasant odor. [4][5] TGA is miscible with polar organic solvents. [6][7]
Infobox references. Glyoxylic acid or oxoacetic acid is an organic compound. Together with acetic acid, glycolic acid, and oxalic acid, glyoxylic acid is one of the C 2 carboxylic acids. It is a colourless solid that occurs naturally and is useful industrially.
PLGA, PLG, or poly (lactic-co-glycolic) acid (CAS: 26780-50-7 ) is a copolymer which is used in a host of Food and Drug Administration (FDA) approved therapeutic devices, owing to its biodegradability and biocompatibility. [1] PLGA is synthesized by means of ring-opening co-polymerization of two different monomers, the cyclic dimers (1,4 ...
Indole-3-acetic acid (IAA, 3-IAA) is the most common naturally occurring plant hormone of the auxin class. It is the best known of the auxins, and has been the subject of extensive studies by plant physiologists. [1] IAA is a derivative of indole, containing a carboxymethyl substituent. It is a colorless solid that is soluble in polar organic ...
The glyoxylate cycle, a variation of the tricarboxylic acid cycle, is an anabolic pathway occurring in plants, bacteria, protists, and fungi. The glyoxylate cycle centers on the conversion of acetyl-CoA to succinate for the synthesis of carbohydrates. [1] In microorganisms, the glyoxylate cycle allows cells to use two carbons (C2 compounds ...
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