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  2. Cardiac cycle - Wikipedia

    en.wikipedia.org/wiki/Cardiac_cycle

    See media help. The cardiac cycle is the performance of the human heart from the beginning of one heartbeat to the beginning of the next. [1] It consists of two periods: one during which the heart muscle relaxes and refills with blood, called diastole, following a period of robust contraction and pumping of blood, called systole. [1]

  3. Diastole - Wikipedia

    en.wikipedia.org/wiki/Diastole

    Diastole (/ daɪˈæstəli / dy-AST-ə-lee) is the relaxed phase of the cardiac cycle when the chambers of the heart are refilling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventricular diastole the relaxing of the ventricles.

  4. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    Diastolic dysfunction is associated with a reduced compliance, or increased stiffness, of the ventricle wall. This reduced compliance results in an inadequate filling of the ventricle and a decrease in the end-diastolic volume. The decreased end-diastolic volume then leads to a reduction in stroke volume because of the Frank-Starling mechanism. [1]

  5. End-diastolic volume - Wikipedia

    en.wikipedia.org/wiki/End-diastolic_volume

    In cardiovascular physiology, end-diastolic volume (EDV) is the volume of blood in the right or left ventricle at end of filling in diastole which is amount of blood present in ventricle at the end of diastole. [1] Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload, which refers to the ...

  6. Cardiac output - Wikipedia

    en.wikipedia.org/wiki/Cardiac_output

    EF is the fraction of blood ejected by the left ventricle (LV) during the contraction or ejection phase of the cardiac cycle or systole. Prior to the start of systole, during the filling phase , the LV is filled with blood to the capacity known as end diastolic volume (EDV). During systole, the LV contracts and ejects blood until it reaches its ...

  7. Preload (cardiology) - Wikipedia

    en.wikipedia.org/wiki/Preload_(cardiology)

    Heart during ventricular diastole. In cardiac physiology, preload is the amount of sarcomere stretch experienced by cardiac muscle cells, called cardiomyocytes, at the end of ventricular filling during diastole. [1] Preload is directly related to ventricular filling. As the relaxed ventricle fills during diastole, the walls are stretched and ...

  8. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    Ventricular relaxation, or diastole, follows repolarization of the ventricles and is represented by the T wave of the ECG. It too is divided into two distinct phases and lasts approximately 430 ms. [1] During the early phase of ventricular diastole, as the ventricular muscle relaxes, pressure on the remaining blood within the ventricle begins ...

  9. Ejection fraction - Wikipedia

    en.wikipedia.org/wiki/Ejection_fraction

    Ejection fraction. An ejection fraction (EF) is the volumetric fraction (or portion of the total) of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat). It can refer to the cardiac atrium, [1] ventricle, [2] gall bladder, [3] or leg veins, [4] although if unspecified it usually refers to the ...

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