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Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy. Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society.
Patients with generalized convulsive seizures that are frequent or separated by a period of significantly impaired consciousness (ie, status epilepticus) or who are medically unstable require immediate assessment and treatment in an acute care setting (emergency department or intensive care unit).
Status epilepticus presents in several forms: 1) convulsive status epilepticus consisting of repeated generalized tonic– clonic (GTC) seizures with persistent postictal depression of neurologic function between seizures; 2) nonconvulsive status epilepticus where seizures produce a continuous or fluctuat-ing “epileptic twilight” state; and 3) rep...
The goal of this current guideline is to provide evidence-based answers to efficacy, safety, and tolerability questions regarding the treatment of convulsive status epilepticus and to synthesize these answers into a treatment algorithm.
Status epilepticus (SE) defined as continuous epileptic activity, is a major medical and neurological emergency requiring immediate treatment to avoid severe morbidity and mortality. All types of epileptic seizures, including focal and absence seizures, can turn into SE, but the most common and serious form of SE is generalized convulsive SE.
Status epilepticus (SE) requires emergent, targeted treat-ment to reduce patient morbidity and mortality. Controversies about how and when to treat SE have been described in the literature [1–3].
Objective: To analyze efficacy, tolerability and safety data for anticonvulsant treatment of children and adults with convulsive status epilepticus and use this analysis to develop an evidence-based treatment algorithm.
The guideline, which reviewed all available adult and pediatric evidence, provides a treatment algorithm that comprises three phases of treatment. It also offers evidence-based answers to the effectiveness, safety and tolerability questions regarding the treatment of convulsive status epilepticus.
Guideline. Introduction. Status epilepticus (SE) requires emergent, targeted treat-ment to reduce patient morbidity and mortality. Controversies about how and when to treat SE have been described in the literature [1–3].
The guideline's recommendations aim to help clinicians worldwide understand the relevant existing evidence for treatment of patients with status epilepticus. The guideline is intended for use by individual clinicians, hospitals, health authorities, and providers.