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  2. Mycobacterium tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Mycobacterium_tuberculosis

    Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .

  3. Tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Tuberculosis

    M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell. The primary site of infection in the lungs, known as the Ghon focus, is generally located in either the upper part of the lower lobe, or the lower part of the upper lobe. [13] Tuberculosis of the lungs may also occur via infection from the blood ...

  4. Ghon's complex - Wikipedia

    en.wikipedia.org/wiki/Ghon's_complex

    Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. [1] [2] The lesions consist of a Ghon focus along with pulmonary lymphadenopathy within a nearby pulmonary lymph node. A Ghon's complex retains viable bacteria, making them sources of long-term infection, which may reactivate and trigger secondary tuberculosis later in ...

  5. Mycobacterium tuberculosis complex - Wikipedia

    en.wikipedia.org/wiki/Mycobacterium_tuberculosis...

    The Mycobacterium tuberculosis complex (MTC or MTBC) is a genetically related group of Mycobacterium species that can cause tuberculosis in humans or other animals. It includes: Mycobacterium tuberculosis; Mycobacterium africanum; Mycobacterium orygis [1] Mycobacterium bovis and the Bacillus Calmette–Guérin strain; Mycobacterium microti ...

  6. Multidrug-resistant tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Multidrug-resistant...

    The resurgence of tuberculosis in the United States, the advent of HIV-related tuberculosis, and the development of strains of TB resistant to the first-line therapies developed in recent decades serve to reinforce the thesis that Mycobacterium tuberculosis, the causative organism, makes its own preferential option for the poor. [66]

  7. Mycolic acid - Wikipedia

    en.wikipedia.org/wiki/Mycolic_acid

    Most attention have been traditionally devoted to the mycolic acids of Mycobacterium species, which display great variation in length and modifications. Modifications not seen in M. tuberculosis include: [9] Double bonds (cis and trans), in M. smegmatis (with a branch from UmaA1) and M. alvei; ω-1 methoxy, in M. alvei; trans-epoxy group, in M ...

  8. Cord factor - Wikipedia

    en.wikipedia.org/wiki/Cord_factor

    Cord factor, or trehalose dimycolate (TDM), is a glycolipid molecule found in the cell wall of Mycobacterium tuberculosis and similar species. It is the primary lipid found on the exterior of M. tuberculosis cells. [1] Cord factor influences the arrangement of M. tuberculosis cells into long and slender formations, giving its name. [2]

  9. Tuberculous pericarditis - Wikipedia

    en.wikipedia.org/wiki/Tuberculous_pericarditis

    Tuberculous pericarditis is caused by infection with the bacterial species Mycobacterium tuberculosis. [1] Bacteria enter the body through inhalation and are ingested by white blood cells called macrophages. [1] Surviving bacteria multiply and can spread to other areas of the body.