Search results
Results from the WOW.Com Content Network
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell. The primary site of infection in the lungs, known as the Ghon focus, is generally located in either the upper part of the lower lobe, or the lower part of the upper lobe. [13] Tuberculosis of the lungs may also occur via infection from the blood ...
Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. [1] [2] The lesions consist of a Ghon focus along with pulmonary lymphadenopathy within a nearby pulmonary lymph node. A Ghon's complex retains viable bacteria, making them sources of long-term infection, which may reactivate and trigger secondary tuberculosis later in ...
The Mycobacterium tuberculosis complex (MTC or MTBC) is a genetically related group of Mycobacterium species that can cause tuberculosis in humans or other animals. It includes: Mycobacterium tuberculosis; Mycobacterium africanum; Mycobacterium orygis [1] Mycobacterium bovis and the Bacillus Calmette–Guérin strain; Mycobacterium microti ...
The resurgence of tuberculosis in the United States, the advent of HIV-related tuberculosis, and the development of strains of TB resistant to the first-line therapies developed in recent decades serve to reinforce the thesis that Mycobacterium tuberculosis, the causative organism, makes its own preferential option for the poor. [66]
Most attention have been traditionally devoted to the mycolic acids of Mycobacterium species, which display great variation in length and modifications. Modifications not seen in M. tuberculosis include: [9] Double bonds (cis and trans), in M. smegmatis (with a branch from UmaA1) and M. alvei; ω-1 methoxy, in M. alvei; trans-epoxy group, in M ...
Cord factor, or trehalose dimycolate (TDM), is a glycolipid molecule found in the cell wall of Mycobacterium tuberculosis and similar species. It is the primary lipid found on the exterior of M. tuberculosis cells. [1] Cord factor influences the arrangement of M. tuberculosis cells into long and slender formations, giving its name. [2]
Tuberculous pericarditis is caused by infection with the bacterial species Mycobacterium tuberculosis. [1] Bacteria enter the body through inhalation and are ingested by white blood cells called macrophages. [1] Surviving bacteria multiply and can spread to other areas of the body.