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  2. Insulin-like growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_1

    Low IGF-1 levels are shown to increase the risk of developing type 2 diabetes and insulin resistance. [67] On the other hand, a high IGF-1 bioavailability in people with diabetes may delay or prevent diabetes-associated complications, as it improves impaired small blood vessel function. [67] IGF-1 has been characterized as an insulin sensitizer ...

  3. Cyclic glycine-proline - Wikipedia

    en.wikipedia.org/wiki/Cyclic_glycine-proline

    Cyclic glycine-proline (cGP) is a small neuroactive peptide that belongs to a group of bioactive 2,5-diketopiperazines (2,5-DKPs) and is also known as cyclo-glycine-proline. cGP is a neutral, stable naturally occurring compound and is endogenous to the human body; found in human plasma, breast milk and cerebrospinal fluid.

  4. Insulin-like growth factor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor

    The IGF-1 receptor is the "physiological" receptor. IGF-1 binds to it at significantly higher affinity than it binds the insulin receptor. Like the insulin receptor, the IGF-1 receptor is a receptor tyrosine kinase—meaning the receptor signals by causing the addition of a phosphate molecule on particular tyrosines. The IGF-2 receptor only ...

  5. Ibutamoren - Wikipedia

    en.wikipedia.org/wiki/Ibutamoren

    Ibutamoren (INN Tooltip International Nonproprietary Name) (developmental code names MK-677, MK-0677, LUM-201, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.

  6. Growth hormone - Wikipedia

    en.wikipedia.org/wiki/Growth_hormone

    GH also stimulates, through the JAK-STAT signaling pathway, [39] the production of insulin-like growth factor 1 (IGF-1, formerly known as somatomedin C), a hormone homologous to proinsulin. [40] The liver is a major target organ of GH for this process and is the principal site of IGF-1 production. IGF-1 has growth-stimulating effects on a wide ...

  7. Management of hair loss - Wikipedia

    en.wikipedia.org/wiki/Management_of_hair_loss

    Dietary isoflavones increase IGF production in scalp dermal papillae in transgenic mice. [95] Topical capsaicin also stimulates IGF at hair follicles via release of vanilloid receptor-1, which in turn leads to more CGRP. [96] Ascorbic acid has led to increased IGF expression in vitro. [97]

  8. Are GLP-1 supplements 'nature's Ozempic'? Doctors evaluate ...

    www.aol.com/news/glp-1-supplements-natures...

    The emerging supplements claim to promote natural production of the GLP-1 hormone, but they undergo far less testing than drugs, said Dr. Hans Schmidt, a bariatric surgeon in New Jersey.

  9. Bone growth factor - Wikipedia

    en.wikipedia.org/wiki/Bone_growth_factor

    A bone growth factor is a growth factor that stimulates the growth of bone tissue. [1] [2]Known bone growth factors include insulin-like growth factor-1 (IGF-1), insulin-like growth factor-2 (IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), parathyroid hormone-related peptide (PTHrP), bone morphogenetic proteins (BMPs ...

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