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Colestyramine or cholestyramine (trade names Questran, Questran Light, Cholybar, Olestyr) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption. It is a strong ion exchange resin , which means it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them ...
Like cholestyramine, colestipol works in the gut by trapping bile acids and preventing them from being reabsorbed. This leads to decreased enterohepatic recirculation of bile acids, increased synthesis of new bile acids by the liver from cholesterol, decreased liver cholesterol, increased LDL receptor expression, and decreasing LDL in blood.
They are occasionally used as an adjunct to the statins as an alternative to the fibrates (another major group of cholesterol-lowering drugs), which are thought to increase the risk of rhabdomyolysis when used with statins. The bile-acid-binding resins can raise triglycerides modestly (about 5%) and cannot be used if the triglycerides are elevated.
They shared their best practices for taking blood pressure medication, including timing and what to do if you miss a dose. Related: The 4 'Non-Negotiables' Everyone Should Adopt for Optimal Health ...
WASHINGTON -- Secret Service agents on Friday officially said goodbye to “Deacon,” the code-name they used for former President Jimmy Carter, who had the longest-serving security detail in the ...
Time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours (τ). Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for concentration of a biological substance (such as a medication ) to decrease from its ...
Before exploring the topic of excessive grooming in cats, it helps to first identify what normal grooming looks like: Oral grooming is the most common way cats groom themselves—cats use their ...
Medications used to slow or stop diarrhea, such as loperamide, may only be used after initiating the treatment. [48] Cholestyramine, an ion-exchange resin, is effective in binding both toxin A and B, slowing bowel motility, and helping prevent dehydration. [82] Cholestyramine is recommended with vancomycin.