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  2. Lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Lymphocytosis

    In adults, absolute lymphocytosis is present when the lymphocyte count is greater than 5000 per microliter (5.0 x 10 9 /L), in older children greater than 7000 per microliter and in infants greater than 9000 per microliter. [1] Lymphocytes normally represent 20% to 40% of circulating white blood cells. When the percentage of lymphocytes exceeds ...

  3. T-cell prolymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/T-cell_prolymphocytic_leukemia

    A high lymphocyte count (> 100 x 10 9 /L) along with low amounts of red blood cells and platelets in the blood are common findings. HTLV-1 serologies are negative, and serum immunoglobins are within normal limits with no paraproteins present. [1]

  4. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Normal B lymphocytes consist of a stew of different antibody-producing cells, resulting in a mixture of both kappa- and lambda-expressing cells. The lack of the normal distribution of these B cells is one basis for demonstrating clonality, the key element for establishing a diagnosis of any B cell malignancy (B cell non-Hodgkin lymphoma). [42]

  5. White blood cell differential - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell_differential

    A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...

  6. Large granular lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Large_granular_lymphocytic...

    As the name suggests, T-cell large granular lymphocyte leukemia is characterized by involvement of cytotoxic-T cells). [2] In a study based in the US, the average age of diagnosis was 66.5 years [3] whereas in a French study the median age at diagnosis was 59 years (with an age range of 12–87 years old). [4]

  7. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    Leukemia (also spelled leukaemia; pronounced / l uː ˈ k iː m iː ə / [1] loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. [9] These blood cells are not fully developed and are called blasts or leukemia cells. [2]

  8. CD19 - Wikipedia

    en.wikipedia.org/wiki/CD19

    Since CD19 is a marker of B cells, the protein has been used to diagnose cancers that arise from this type of cell - notably B cell lymphomas, acute lymphoblastic leukemia , and chronic lymphocytic leukemia . [8] The majority of B cell malignancies express normal to high levels of CD19.

  9. Leukemoid reaction - Wikipedia

    en.wikipedia.org/wiki/Leukemoid_reaction

    Conventionally, a leukocytosis exceeding 50,000 WBC/mm 3 with a significant increase in early neutrophil precursors is referred to as a leukemoid reaction. [2] The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature neutrophil precursors, in contrast to the immature forms typically seen in acute leukemia.