Search results
Results from the WOW.Com Content Network
Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Celgene was originally a unit of Celanese.In 1986, Celanese completed the corporate spin-off of Celgene following the merger of Celanese with American Hoechst. [3] [4]In August 2000, Celgene acquired Signal Pharmaceuticals, Inc., a privately held company that developed pharmaceuticals to regulate disease-related genes. [5]
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
2006 North American E. coli O157:H7 outbreak in spinach; 2006 North American E. coli O157:H7 outbreaks; 2008 United States salmonellosis outbreak; 2009 swine flu pandemic in the United States; 2011 United States listeriosis outbreak; 2012 outbreak of Salmonella; 2012–2013 flu season; 2014 enterovirus D68 outbreak; 2015 Bronx Legionnaires ...
Chin J. B., ed. Control of Communicable Diseases Manual. 17th ed. APHA [American Public Health Association] Press; 2000. ISBN 978-0-87553-189-2; Red Book: 2009 Report of the Committee on Infectious Diseases. 2009. American Academy of Pediatrics. 28th ed. ISBN 978-1-58110-306-9; Centers for Disease Control and Prevention. CDC Works 24/7 ...
Revlimid Small molecule Multiple myeloma. Myelodysplastic syndromes. Celgene: 5,801 821 10 Sofosbuvir: Sovaldi Small molecule Hepatitis C: Gilead Sciences: 5,276 (5,007) 11 Fluticasone propionate/salmeterol: Seretide Advair Small molecule Asthma. Chronic obstructive pulmonary disease. GlaxoSmithKline: 5,227 (778) 12 Rosuvastatin: Crestor Small ...
Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. [6] It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).