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Nephritic syndrome is a syndrome comprising signs of nephritis, which is kidney disease involving inflammation. It often occurs in the glomerulus, where it is called glomerulonephritis. Glomerulonephritis is characterized by inflammation and thinning of the glomerular basement membrane and the occurrence of small pores in the podocytes of the ...
The syndrome presents in different ways in the two groups: the most frequent glomerulopathy in children is minimal change disease (66% of cases), followed by focal segmental glomerulosclerosis (8%) and mesangiocapillary glomerulonephritis (6%). [24] In adults the most common disease is mesangiocapillary glomerulonephritis (30-40%), followed by ...
Adults with a new onset of glomerulonephrosis can be treated with prednisone. In children with Minimal Change Disease and adults relapsing into glomerulonephrosis, prednisolone is commonly used until proteinuria is no longer present, but children have a much quicker remission than adults and are less prone to relapse. [ 16 ]
In adults, there are numerous potential causes, which makes an early kidney biopsy necessary to determine the correct diagnosis and treatment plan. [4] It also differs from the nephrotic syndrome that often develops in young individuals with childhood-onset systemic lupus erythematosus , i.e., cSLE. cSLE is a form of systemic lupus ...
Membranoproliferative glomerulonephritis (MPGN) is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane thickening, [2] activating the complement system and damaging the glomeruli. MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults. [3]
Minimal change disease (MCD), also known as lipoid nephrosis or nil disease, among others, is a disease affecting the kidneys which causes nephrotic syndrome. [1] Nephrotic syndrome leads to the loss of significant amounts of protein to the urine (proteinuria), which causes the widespread edema (soft tissue swelling) and impaired kidney function commonly experienced by those affected by the ...
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In adults, the signs and symptoms of infection may still be present at the time when the kidney problems develop, and the terms infection-related glomerulonephritis or bacterial infection-related glomerulonephritis are also used. [6] Acute glomerulonephritis resulted in 19,000 deaths in 2013, down from 24,000 deaths in 1990 worldwide. [7]
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