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Parkinson's typically manifests in individuals over 60, with about one percent affected. In those younger than 50, it is termed "early-onset PD". No cure for Parkinson's is known, and treatment focuses on alleviating symptoms. Initial treatment typically includes L-DOPA, MAO-B inhibitors, or dopamine agonists.
Veronica Brown lived with chronic fatigue, depression, and anxiety for over 10 years before she learned they were early signs of Parkinson's disease. Here's how she found relief after diagnosis.
Parkinson's disease patient showing a typical flexed walking posture in advanced stage. Signs and symptoms of Parkinson's disease are varied. Parkinson's disease affects movement, producing motor symptoms. [1] Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are also ...
Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Parkinsonism gait problems can lead to falls and serious physical injuries. Other common symptoms include:
New research reports that everyday smartwatches and smartphones could potentially be used to measure changes in Parkinson's symptoms over time in people in the early stages of the disease.
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[5] [6] By the time motor symptoms appear and treatment is initiated, there is already over 50% dopaminergic neuronal cell loss in the substantia nigra. [6] [13] Therefore, non-motor symptoms are valuable biomarkers of early stages of PD and provide a potential avenue for early disease diagnosis and early intervention. [14] [15]
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