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The gut-brain axis is a two-way communication network within human systems that correlates the gut microbiome and the brain, encompassing immune, endocrine and neural connections. There is an evident association between the gastrointestinal tract and enteric microbiota with functional changes highlighted in the nervous system evidenced in vivo ...
The gut–brain axis is the two-way biochemical signaling that takes place between the gastrointestinal tract (GI tract) and the central nervous system (CNS). [2] The term "microbiota–gut–brain axis" highlights the role of gut microbiota in these biochemical signaling.
The gut–brain axis is the biochemical signaling that takes place between the gastrointestinal tract and the central nervous system. [75] That term has been expanded to include the role of the gut flora in the interplay; the term "microbiome––brain axis" is sometimes used to describe paradigms explicitly including the gut flora.
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
"Microbiome is a term that describes the genome of all the microorganisms, symbiotic and pathogenic, living in and on all vertebrates. The gut microbiome consists of the collective genome of microbes inhabiting the gut including bacteria, archaea, viruses, and fungi". [70]
The Human Microbiome Handbook. DEStech Publications. ISBN 978-1-605-95159-1. Niall, Hyland; Catherine, Stanton (2016). The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. Academic Press. ISBN 978-0-128-02544-4
Cryan's current research is focused on understanding the interaction between the brain, gut and microbiome, and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan. The Cryan Lab has been a global leader in defining a critical role for the gut microbiome in regulating brain and behavior.
This study highlights the gut microbiome's role in brain function and mental health is a growing research area, particularly during adolescence, a critical period for gut-brain axis development. This study systematically reviewed and analyzed the effects of psychobiotic interventions on anxiety in youth (ages 10–24).