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BCS classes. According to the Biopharmaceutics Classification System (BCS) drug substances are classified to four classes upon their solubility and permeability: [1] Class I – high permeability, high solubility. Example: metoprolol, paracetamol [2] Those compounds are well absorbed and their absorption rate is usually higher than excretion.
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I came to this page knowing virtually knowing about BCS, and have left rather confused. The text seems to first say that there are four classes - based on permeability and solubility. And then says classification based on solubility, permeability and dissolution. I'm left very confused - could anyone clarify?