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Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. [12] [4] [6] [13] It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs.
For comparison, the metabolic clearance rate of estriol is 1,110 L/day/m 2. [5] A single 1 to 2 mg dose of estrone in oil solution by intramuscular injection has a duration of about 2 or 3 days. [ 45 ] [ 67 ] [ 68 ] As an aqueous suspension by intramuscular injection , estrone was used at a dose of 0.1 to 0.5 mg 2 to 3 times per week, or at a ...
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[11] [154] Given by subcutaneous injection in mice, estradiol is about 10-fold more potent than estrone and about 100-fold more potent than estriol. [ 154 ] The ERs are expressed widely throughout the body, including in the breasts , uterus , vagina , fat , skin , bone , liver , pituitary gland , hypothalamus , and other parts of the brain . [ 27 ]
Estradiol valerate (EV), sold for use by mouth under the brand name Progynova and for use by injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen medication.
Estriol succinate, also known as estriol disuccinate or as estriol 16α,17β-di(hydrogen succinate), is a synthetic estrane steroid and a derivative of estriol. [7] [29] [30] It is specifically the C16α and C17β disuccinate ester of estriol. [7] [29] [30] [1] The medication is provided both as estriol succinate and as estriol sodium succinate ...
Administration of a rectal suppository containing 100 mg estriol resulted in estriol levels in pregnant women at term increasing by about 53%. [266] Estriol levels at term are normally between 5,000 and 20,000 pg/mL, which suggests that estriol levels may have increased following the suppository by about 5,000 to 10,000 pg/mL (precise levels ...
Topical hydrocortisone is formulated as liquid, solution, lotion, cream, gel, ointment, foam, and spray. [33] The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [ 12 ]
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