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Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. [ 5 ] [ 6 ] [ 7 ] It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. [ 6 ]
[74] [75] [76] One study found a 44% reduction in bloodstream infection rates when universal decolonization was used (e.g. intranasal mupirocin ointment and chlorhexidine body wash) in a trial involving 73,256 hospital patients. [72]
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [1] The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions, including insect bites and stings ...
Although S. aureus can be present on the skin of the host, a large proportion of its carriage is through the anterior nares of the nasal passages [2] and can further be present in the ears. [129] The ability of the nasal passages to harbour S. aureus results from a combination of a weakened or defective host immunity and the bacterium's ability ...
Treatment is typically with antibiotic creams such as mupirocin or fusidic acid. [3] [5] Antibiotics by mouth, such as cefalexin, may be used if large areas are affected. [3] Antibiotic-resistant forms have been found. [3] Healing generally occurs without scarring. [7] Impetigo affected about 140 million people (2% of the world population) in ...
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Antibiotics by mouth are not recommended unless the person has poor immune function or there is infection of the skin around the ear. [2] Typically, improvement occurs within a day of the start of treatment. [2] Treatment of chronic cases depends on the cause. [2] Otitis externa affects 1–3% of people a year; more than 95% of cases are acute. [2]