Search results
Results from the WOW.Com Content Network
A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...
The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.
Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...
Neutral evolution can therefore be visualised as a population diffusing from one set of sequence nodes, through the neutral network, to another cluster of sequence nodes. Since the majority of evolution is thought to be neutral, [ 14 ] [ 15 ] a large proportion of gene change is the movement though expansive neutral networks.
Neutral theory of molecular evolution [31] 1968 Kimura, Motoo: Yes Genetic drift: Yes Yes Only at molecular level; fits in with natural selection at higher levels. Observed 'molecular clock' supports neutral drift; not a rival to natural selection, as does not cause evolution of phenotype: Darwinian evolution [32] 1859 Darwin, Charles: Yes ...
Neutral theory – Theory of evolution by changes at the molecular level; Shifting balance theory – One version of the theory of evolution; Price equation – Description of how a trait or gene changes in frequency over time; Coefficient of relationship – Mathematical guess about inbreeding; Fitness – Expected reproductive success
Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution.
According to the neutral theory of molecular evolution, an idealised diploid population will have a pairwise nucleotide diversity equal to 4 N e, where is the mutation rate. The effective population size can therefore be estimated empirically by dividing the nucleotide diversity by 4 μ {\displaystyle \mu } . [ 5 ]