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  2. Things You Probably Don't Know About Viagra (Like What ... - AOL

    www.aol.com/things-probably-dont-know-viagra...

    Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...

  3. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]

  4. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    Certain medications for heart disease If you experience severe side effects after using Viagra or other ED medication, it’s important to seek medical advice and assistance as soon as possible ...

  5. How to Get Better Viagra Results in 2025 - AOL

    www.aol.com/better-viagara-results-2025...

    Viagra is great as an ED treatment, but taking it in particular conditions can make it even more effective. ... People with heart disease, high blood pressure, obesity, and other health conditions ...

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra. It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, in the year 2005, it was approved for the treatment of pulmonary arterial hypertension. [2] Vardenafil and tadalafil were discovered in 1990.

  8. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

    www.aol.com/does-viagra-actually-intimate...

    Today, Viagra and its active ingredient sildenafil is still prescribed for pulmonary arterial hypertension (under the name Revatio), but it’s mostly and most popularly known for its powers ...

  9. Drug repositioning - Wikipedia

    en.wikipedia.org/wiki/Drug_repositioning

    A number of successes have been achieved, the foremost including sildenafil (Viagra) for erectile dysfunction and pulmonary hypertension and thalidomide for leprosy and multiple myeloma. [3] [5] Clinical trials have been performed on posaconazole and ravuconazole for Chagas disease. [6]

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