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Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
In all adults, including seniors, a normal resting heart rate can be anywhere between 60 and 100 beats per minute. But note: the lower the number within this range, the better.
It is one of the two most common valvular heart diseases in the elderly, [27] and the commonest type of valvular heart disease in low and middle income countries. [3] In a study of 595 male elite football players aged 18–38 and 47 sedentary non-athletes, mitral regurgitation was found in 20% football players and 15% in control group. Football ...
Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias.
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
A study in 2000 found that long-term benzodiazepine therapy does not result in brain abnormalities. [75] Withdrawal from high-dose use of nitrazepam anecdotally was alleged in 2001 to have caused severe shock of the whole brain with diffuse slow activity on EEG in one patient after 25 years of use. After withdrawal, abnormalities in hypofrontal ...
Bradycardia, also called bradyarrhythmia, is a resting heart rate under 59 beats per minute (BPM). [1] While bradycardia can result from various pathologic processes, it is commonly a physiologic response to cardiovascular conditioning or due to asymptomatic type 1 atrioventricular block.
Palpitation may be associated with coronary heart disease, perimenopause, hyperthyroidism, adult heart muscle diseases like hypertrophic cardiomyopathy, congenital heart diseases like atrial septal defects, [4] [2] diseases causing low blood oxygen such as asthma, emphysema or a blood clot in the lungs; previous chest surgery; [2] kidney ...