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For example, lowering your LDL cholesterol by 1 millimole per liter (mmol/L) can reduce your risk of major vascular events by about 20 percent — regardless of your initial LDL level.
According to the 2015 Cochrane systematic review, atorvastatin showed greater cholesterol-lowering effect in women than in men compared to rosuvastatin. [49] In children, statins are effective at reducing cholesterol levels in those with familial hypercholesterolemia. [50] Their long term safety is, however, unclear.
Some people don’t experience any symptoms at all. Symptoms common in several types of cardiovascular disease include: Shortness of breath. Chest pain. Fatigue. Dizziness. Fainting. Fever ...
A review of your symptoms. You might receive blood tests to look for risk factors for atherosclerosis. Blood tests might check your: Cholesterol levels. Triglyceride and lipid levels. Blood sugar ...
Meta-analysis showed that rosuvastatin can modestly increase levels of high-density lipoprotein (HDL) cholesterol, as well as with other statins. [12] A 2014 Cochrane review determined there was good evidence for rosuvastatin lowering non-HDL levels linearly with dose.
Conversely, these antibodies are absent in people who take statin medications but do not have myopathy. Thus, the presence of anti-HMG CoA reductase antibodies in someone who uses a statin and has myopathy strongly supports the diagnosis. [3] CK levels increase to 10-100 times above normal (2000–20,000 IU/L) in more than 90% of cases.
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